Hydrochloric Acid → 2,4-Dichloro-6-methyl-1,3,5-triazine

Participants

Reaction Conditions

Reaction Steps

To a 1 l flask equipped with a mechanical stirrer, a reflux condenser, a thermometer and a gas inlet was charged 500 ml of methyl acetate and 50 g of sodium dicyanamide. At room temperature, 80 g of HCl gas was charged. After stirring for 15 minutes, 88 g of acetyl chloride was added in one portion. The reaction mixture was heated to reflux for 3 hours. It was then cooled to 10° C. and poured into 500 ml of ice water. Extraction with methyl acetate and subsequent drying and evaporation afforded 32 g of 2,4-dichloro-6-methyl-1,3,5-triazine. The yield was 37%.

Provenance & Evidence