Ammonia → HCID 14748923, compound

HRID 2371909Notes

Reaction equation

HRID 2371909 reaction equation
C([O:3][C:4]([C:6]1[S:7][C:8]2[C:15]([CH3:16])=[CH:14][C:13]([N+:17]([O-:19])=[O:18])=[CH:12][C:9]=2[N+:10]=1[O-:11])=O)C.[NH3:20]>CO>[C:4]([C:6]1[S:7][C:8]2[C:15]([CH3:16])=[CH:14][C:13]([N+:17]([O-:19])=[O:18])=[CH:12][C:9]=2[N+:10]=1[O-:11])(=[O:3])[NH2:20]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 13040090HCID 13040090, compound

Product 1

HCID 14748923HCID 14748923, compoundYield 97%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

160 g (0.57 mol) of 2-ethoxycarbonyl-5-nitro-7-methyl-benzothiazole-N-oxide are initially introduced in 1.0 1 of methanol, 42 g (0.62 mol of NH:) of an aqueous ammonia solution are added and the mixture is stirred at 20° C. to 25° C. for 5 hours. The crystalline product is isolated by filtering off with suction. 140 g (96 % of theory) of 2-carbamyl-5-nitro-7-methyl-benzothiazole-N-oxide of melting point >250° C. are obtained.

Workup

  1. additionare added
  2. customThe crystalline product is isolated
  3. filtrationby filtering off with suction

Sources & evidence

ORD record
ord-a1e5d1887bfb40439f9f65fb78cb6a67
Source dataset
uspto-grants-1992_03
Patent number
US05096910

Reaction notes

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