2-Methylbenzoyl chloride → 6-(2-Methylbenzoyl)-(6H)-dibenz[c,e][1,2]oxaphosphorin 6-oxide
Reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4](Cl)=[O:5].C[O:12][P:13]1[C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=2[C:16]2[CH:23]=[CH:24][CH:25]=[CH:26][C:15]=2[O:14]1>CC(C)=O>[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([P:13]1(=[O:12])[C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=2[C:16]2[CH:23]=[CH:24][CH:25]=[CH:26][C:15]=2[O:14]1)=[O:5]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 115 °C
Procedure
61.8 g (0.4 mol) of 2-methylbenzoyl chloride were warmed to 80° C. under a nitrogen atmosphere. 92 g (0.4 mol) of 6-methoxy-(6H)-dibenz[c,e][1,2]-oxaphosphorin were added dropwise over the course of two to three hours while stirring. The temperature was then increased in steps to 115° C. When the reaction was complete, 50 ml of acetone were added at room temperature. After crystallization, 103 g (77% of theory) of the above-mentioned compound of melting point 102° to 104° C. were obtained.
Workup
- customAfter crystallization, 103 g (77% of theory) of the above-mentioned compound of melting point 102° to 104° C.
- customwere obtained
Sources & evidence
- ORD record
- ord-a48ef47c8de747b4a8f4bb9592be2e76
- Source dataset
- uspto-grants-1992_03
- Patent number
- US05096935
Reaction notes
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