2-Chlorobenzoyl chloride → HCID 14366292, compound

HRID 2371993Notes

Reaction equation

[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4](Cl)=[O:5].C[O:12][P:13]1[C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=2[C:16]2[CH:23]=[CH:24][CH:25]=[CH:26][C:15]=2[O:14]1>C1(C)C=CC=CC=1>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([P:13]1(=[O:12])[C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=2[C:16]2[CH:23]=[CH:24][CH:25]=[CH:26][C:15]=2[O:14]1)=[O:5]

Participants

Conditions

Temperature: 60 °C

Procedure

52.5 g (0.3 mol) of 2-chlorobenzoyl chloride were warmed to 80° C. under a nitrogen atmosphere. 69 g (0.3 mol) of 6-methoxy-(6H)-dibenz[c,e][1,2]oxaphosphorin were added dropwise while stirring. During the dropwise addition, the mixture was cooled to 60° C., and the temperature was then kept at 60°-70° C. When the reaction was complete, 40 ml of toluene were added at 45° C. 92 g (89% of theory) of the abovementioned compound of melting point 108° to 110° C. were obtained.

Workup

additionDuring the dropwise addition
customwas then kept at 60°-70° C
custom92 g (89% of theory) of the abovementioned compound of melting point 108° to 110° C. were obtained

Sources & evidence

ORD record: ord-abbd76f748094ab88beb2c47fce24ceb
Source dataset: uspto-grants-1992_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05096935

Reaction notes

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