HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(phenylmethyl)-N-propyl-3-pyrrolidinemethanamine → N-propyl-3-pyrrolidinemethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(phenylmethyl)-N-propyl-3-pyrrolidinemethanamine | HCID 14280885 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-propyl-3-pyrrolidinemethanamine | HCID 13491799 | 83.2% |
Reaction Steps
A mixture of 14.0 g (60.0 mmole) of 1-(phenylmethyl)-N-propyl-3-pyrrolidinemethanamine, 1.0 g of 20% palladium on carbon and 140 ml of methanol was shaken in an atmosphere of hydrogen at about 4.5×105Pa and room temperature for 24 hours. The catalyst was removed by filtering through Celite, the filtrate concentrated and distilled in vacuo to give 7.1 g of N-propyl-3-pyrrolidinemethanamine, bp 49-50° C./0.25 mm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05097032 |
| Source dataset | uspto-grants-1992_03 |
| ORD ID | ord-4274de7ec53d46ac8c35cc351b382dc1 |
| Source note | uspto-grants-1992_03 |