HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → Methyl 3-(chlorocarbonyl)pyridine-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Methyl 2,3-pyridinedicarboxylate | HCID 98626 | — |
| Product | Methyl 3-(chlorocarbonyl)pyridine-2-carboxylate | HCID 13239660 | — |
Reaction Steps
A mixture of 2-methoxycarbonylnicotinic acid (4.0 g) and thionyl chloride (30 ml) is heated under reflux until homogeneous. The remaining thionyl chloride is distilled off in vacuo to give 2-methoxycarbonylnicotinoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05098462 |
| Source dataset | uspto-grants-1992_03 |
| ORD ID | ord-0a674054ae48429ca299facb44bdd7ba |
| Source note | uspto-grants-1992_03 |