HuagongsheHuagongshe Chemistry Print Report · For research reference only
Selenium Dioxide → Ethyl 2-formylnicotinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Selenium Dioxide | HCID 24007 | — |
| Reactant | Ethyl 2-methylnicotinate | HCID 74401 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | Ethyl 2-formylnicotinate | HCID 15639417 | — |
Reaction Steps
A solution of ethyl 2-methylnicotinate (2.0 g, 12.12 mmol), selenium dioxide (20.0 g, 18.18 mmol) and dioxane (10 ml) is heated at 135° for 4 hours. The reaction mixture is filtered and the filtrate is concentrated and purified by prep. TLC to give ethyl 2-formylnicotinate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05098466 |
| Source dataset | uspto-grants-1992_03 |
| ORD ID | ord-d7a2e87fc5b5468aabf7f1fa901ffd6a |
| Source note | uspto-grants-1992_03 |