Thionyl Chloride → 2-Methyl octanoic acid chloride

Participants

Reaction Steps

To 8.98 g (75.5 mmol) of thionyl chloride placed in a flask was added 8.93 g (56.4 mmol) of the above (+)-2-methyl octanoic acid with stirring at room temperature. Then, the mixture was stirred and reacted at room temperature for 10 minutes, at 30° C. for 20 minutes, at 40° C. for 30 minutes and at 70° C. for 2 hours. Thereafter, an excessive amount of thionyl chloride was distilled off to obtain 9.80 g (55.5 mmol, yield: 98%) of a light brown (+)-2-methyl octanoic acid chloride.

Provenance & Evidence