3'-Fluoro-4'-(octyloxy)[1,1'-biphenyl]-4-carboxylic acid → 3-Fluoro-4-(2-methylnonanoyl) phenyl-3'-fluoro-4'-octyloxybiphenyl-4-carboxylic acid

HRID 2372263Notes

Reaction equation

HRID 2372263 reaction equation
[F:1][C:2]1[CH:3]=[C:4](O)[CH:5]=[CH:6][C:7]=1[C:8](=[O:18])[CH:9]([CH3:17])[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[F:20][C:21]1[CH:22]=[C:23]([C:36]2[CH:41]=[CH:40][C:39]([C:42]([OH:44])=[O:43])=[CH:38][CH:37]=2)[CH:24]=[CH:25][C:26]=1[O:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35]>>[F:1][C:2]1[CH:3]=[C:4]([C:37]2[CH:38]=[C:39]([C:42]([OH:44])=[O:43])[CH:40]=[CH:41][C:36]=2[C:23]2[CH:24]=[CH:25][C:26]([O:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])=[C:21]([F:20])[CH:22]=2)[CH:5]=[CH:6][C:7]=1[C:8](=[O:18])[CH:9]([CH3:17])[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

Participants

3

Reactant 2

HCID 189965163'-Fluoro-4'-(octyloxy)[1,1'-biphenyl]-4-carboxylic acidHCID 54541175(+)-3-Fluoro-4-(2-methylnonanoyl) phenol

Product 1

HCID 1317172053-Fluoro-4-(2-methylnonanoyl) phenyl-3'-fluoro-4'-octyloxybiphenyl-4-carboxylic acid

Procedure

The same procedure as in Example 20 was repeated, except that (+)-3-fluoro-4-(2-methylnonanoyl) phenol was used instead of (+)-3-fluoro-4-(2-methyloctanoyl) phenol in Example 20 and 3'-fluoro-4'-octyloxybiphenyl-4-carboxylic acid was used instead of 3-fluoro-4-heptyloxy benzoic acid in Example 20, to obtain an objective compound having the aforementioned physical and chemical properties.

Workup

  1. customto obtain an objective compound

Sources & evidence

ORD record
ord-4827a61cf2324379a263ecf13de505b5
Source dataset
uspto-grants-1992_03
Patent number
US05098602

Reaction notes

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