HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 178515746, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | Magnesium monoxide | HCID 6850729 | — |
| Reactant | HCID 178515745 | HCID 178515745 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | HCID 178515746 | HCID 178515746 | 29% |
Reaction Steps
50 mg (180 μmole) D-luciferin is dissolved in 2 ml water and mixed with 350 mg (8.75 mmole) magnesium oxide. To the cooled suspension, slowly and drop by drop a solution of 92 mg (600 μmole) phosphoroxychloride in 1 ml carbon tetrachloride is added. It is then allowed to stand for 30 min at room temperature, filtered and neutralized with acetic acid. After concentration, it is purified with HPLC as in Example 3. The yield is 29% of theoretical.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05098828 |
| Source dataset | uspto-grants-1992_03 |
| ORD ID | ord-c00b03bbf0fd4c488478400144ba8257 |
| Source note | uspto-grants-1992_03 |