2-Tert-butyl-4,5-dichloro-2,3-dihydropyridazin-3-one → HCID 19903175, compound

HRID 2372343Notes

Reaction equation

HRID 2372343 reaction equation
[Cl:1][C:2]1[C:3](=[O:13])[N:4]([C:9]([CH3:12])([CH3:11])[CH3:10])[N:5]=[CH:6][C:7]=1Cl.[CH2:14]([N:17]([CH2:21][C:22]1[CH:30]=[CH:29][C:25]([CH2:26][NH:27][CH3:28])=[CH:24][CH:23]=1)[CH2:18][CH2:19][CH3:20])[CH2:15][CH3:16]>>[Cl:1][C:2]1[C:3](=[O:13])[N:4]([C:9]([CH3:12])([CH3:11])[CH3:10])[N:5]=[CH:6][C:7]=1[N:27]([CH2:26][C:25]1[CH:29]=[CH:30][C:22]([CH2:21][N:17]([CH2:14][CH2:15][CH3:16])[CH2:18][CH2:19][CH3:20])=[CH:23][CH:24]=1)[CH3:28]

Participants

3

Reactant 2

HCID 27822252-Tert-butyl-4,5-dichloro-2,3-dihydropyridazin-3-oneHCID 19903155HCID 19903155, compound

Product 1

HCID 19903175HCID 19903175, compound

Procedure

The compounds as identified in Table 15 were prepared in the synthetic manner and after-treatment similar to those in Example 8 except that the 4,5-dichloro-2-alkyl- 3(2H)pyridazinones with R1 and R2 as identified in Table 15 were used instead of the starting 4,5-dichloro-2-t-butyl-3(2H)pyridazinone used in Example 8, and the N-alkylbenzylamines with R3, Y1, Y2 and Y3 as identified in Table 15 were used instead of the starting 4-di-n-propylaminomethyl-N-methylbenzylamine. In the NMR data, only the characteristic absorptions are given in Table 15.

Workup

  1. customwere prepared in the synthetic manner

Sources & evidence

ORD record
ord-681b43d8f7864163892b024ccf670553
Source dataset
uspto-grants-1992_03
Patent number
US05098900

Reaction notes

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