反应详情

The hydrazone (16.0 g, 68 mmol) derived from p-methoxyacetophenone and ethylcarbazate was added to 50 ml of SOCl2 and cooled in an ice bath. The reaction was warmed to room temperature and then heated at 60° C. for 1 hour. The reaction was cooled, and the solvent was removed under vacuum, affording a crude solid. The solid was recrystallized from ether affording 4 (9.95 g, 76%), m.p. 91°-93.5° C.

1. temperaturecooled in an ice bath
2. temperatureheated at 60° C. for 1 hour
3. temperatureThe reaction was cooled
4. customthe solvent was removed under vacuum
5. customaffording a crude solid
6. customThe solid was recrystallized from ether affording 4 (9.95 g, 76%), m.p. 91°-93.5° C.