HCID 13427187, compound → HCID 13427193, compound

Participants

Reaction Steps

Thiadiazole 36 (11.8 g, 36.1 mmol) in EtOH (200 ml) was hydrogenated over 5% Pd/C (3.6 g) at 50 psi for 16 hours. The solution was filtered through a celite pad and washed with EtOH. The solvent was removed under reduced pressure, and the crude solid was recrystallized from EtOAc/MeOH to afford 32 (9.2 g, 95.1%), m.p. 236° C. (decomposes).

Provenance & Evidence