Dimethylamine → HCID 57314618, compound

HRID 2372381Notes

Reaction equation

HRID 2372381 reaction equation
[CH:1]([O:4][C:5]([C:7]1[CH2:8][CH2:9][N:10]2[C:14](=[CH:15][C:16](SC3C=CC=CC=3)=[O:17])[CH2:13][S:12][C:11]=12)=[O:6])([CH3:3])[CH3:2].[CH3:25][NH:26][CH3:27]>>[CH3:25][N:26]([CH3:27])[C:16](=[O:17])[CH:15]=[C:14]1[CH2:13][S:12][C:11]2=[C:7]([C:5]([O:4][CH:1]([CH3:3])[CH3:2])=[O:6])[CH2:8][CH2:9][N:10]12

Participants

3

Reactant 2

HCID 674DimethylamineHCID 86745568HCID 86745568, compound

Product 1

HCID 57314618HCID 57314618, compound

Procedure

1.0 g of S-phenyl (7-isopropoxycarbonyl-2,3,5,6-tetrahydropyrrolo[2,1-b]thiazol-3-ylidene)thioacetate was suspended in 10 ml of a 40% aqueous solution of dimethylamine and stirred at room temperature for 1 hour. After distilling off the excessive dimethylamine, the obtained crude crystals were recrystallized from isopropyl alcohol. Thus 0.7 g of the title compound was obtained as crystals.

Workup

  1. distillationAfter distilling off the excessive dimethylamine
  2. customthe obtained crude crystals
  3. customwere recrystallized from isopropyl alcohol

Sources & evidence

ORD record
ord-0dd4e80f9fb9406987d463029c840cbe
Source dataset
uspto-grants-1992_03
Patent number
US05098919

Reaction notes

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