反应详情

To 1.50 g of 4-nitrophenyl (7-isopropoxycarbonyl-6-methyl-2,3,5,6-tetrahydropyrrolo[2,1-b]thiazol-3-ylidene)acetate, was added 40 ml of a 25% aqueous solution of dimethylamine and the mixture was stirred at room temperature for 3 days. 40 ml of water was added thereto and the precipitate thus formed was collected by filtration, washed with water and dissolved in chloroform. After drying and distilling off the solvent, the crude crystals thus obtained were recrystallized from a solvent mixture of ether and n-hexane. Thus 0.6 g of the title compound was obtained.

1. customthe precipitate thus formed
2. filtrationwas collected by filtration
3. washwashed with water
4. dissolutiondissolved in chloroform
5. customAfter drying
6. distillationdistilling off the solvent
7. customthe crude crystals thus obtained
8. customwere recrystallized from a solvent mixture of ether and n-hexane