Water → HCID 19904408, compound

HRID 2372411Notes

Reaction equation

HRID 2372411 reaction equation
CC1(C)[O:7][CH2:6][C:5]([CH2:12][CH3:13])([CH:8]([OH:11])[CH2:9][CH3:10])[CH2:4][O:3]1.O>CO>[CH2:12]([C:5]([CH2:6][OH:7])([CH:8]([OH:11])[CH2:9][CH3:10])[CH2:4][OH:3])[CH3:13]

Participants

4

Reactant 2

HCID 962WaterHCID 19904387HCID 19904387, compound

Product 1

HCID 19904408HCID 19904408, compoundYield 74.8%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2,2-Dimethyl-5-ethyl-5-(1-hydroxypropyl)-1,3-dioxane (10 g.) and Dowex 50×8-200 ion exchange resin (H+ form) (1.0 g.) in methanol (200ml) containing water (40 ml) was refluxed with stirring for three hours. The mixture was filtered and the filtrate was evaporated in vacuo. 2-Ethyl-2-hydroxymethyl-pentan-1,3-diol (6.0 g.) was obtained as a colourless viscous oil.

Workup

  1. temperaturewas refluxed
  2. filtrationThe mixture was filtered
  3. customthe filtrate was evaporated in vacuo

Sources & evidence

ORD record
ord-c82d080072e94d66b7e41d0704fb484d
Source dataset
uspto-grants-1992_03
Patent number
US05098929

Reaction notes

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