2-Naphthalenemethanol → HCID 20080624, compound

HRID 2372475Notes

Reaction equation

HRID 2372475 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][OH:12].F[C:14]1[CH:15]=[C:16]([Br:24])[CH:17]=[C:18]([C:20]([F:23])([F:22])[F:21])[CH:19]=1>>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][O:12][C:14]1[CH:15]=[C:16]([Br:24])[CH:17]=[C:18]([C:20]([F:22])([F:21])[F:23])[CH:19]=1

Participants

3

Reactant 2

HCID 741282-NaphthalenemethanolHCID 27363233-Bromo-5-fluorobenzotrifluoride

Product 1

HCID 20080624HCID 20080624, compoundYield 80%

Procedure

Using the procedure described in the first paragraph of Note e. below Table IV in Example 15, 2-naphthalenemethanol was reacted with 3-fluoro-5-trifluoromethylbromobenzene to give 3-(naphth-2-ylmethoxy)-5-trifluoromethylbromobenzene (80%), m.p. 68°-70° C.

Sources & evidence

ORD record
ord-19b38276a75147f981b2c98eba02d97b
Source dataset
uspto-grants-1992_03
Patent number
US05098930

Reaction notes

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