Trifluoroacetic acid → HCID 67918753, compound

Participants

Reaction Steps

Bromomethylbenzoyl-glycine. t-butyl ester was treated with trifluoroacetic acid and the product, a solid melting at 162°-164°, was purified in 70% yield by preparative thin layer chromatography. NMR (CHCl3) δ 8.86 (t, 1H, NH, J=5.8 Hz), 7.86 (d, 2H, Ar-2,6), 7.53 (d, 2H, Ar-3,5), 4.81 (s, 2H, CH2Br), 3.91 (d, 2 H, J=5.9 Hz), 3.6 (br, 1H, COOH).

Provenance & Evidence