Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 1-(1,4-Dioxaspiro[4.4]non-6-ylmethyl)-1H-imidazole | HCID 10846044 | — |
| Product | HCID 10702167 | HCID 10702167 | — |
Reaction Steps
In an oil bath, 3.5603 g of 2-(lH-imidazol-1-ylmethyl)cyclopentanone ethyleneketal (IV) and 17.8 ml of 2N hydrochloric acid added thereto were stirred at 60° C for 5 hours. The resultant reaction solution was left cooling. Then, it was neutralized with an aqueous lN potassium hydroxide solution and extracted with methylene chloride, to obtain an organic layer. This organic layer was washed with water, dried over anhydrous sodium sulfate, and evaporated under a reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05099029 |
|---|
| Source dataset | uspto-grants-1992_03 |
|---|
| ORD ID | ord-6dd9dd3761954a08b8bd6210cc5dcde5 |
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| Source note | uspto-grants-1992_03 |
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