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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 237255Generated: October 29, 2026

[6-(Trifluoromethyl)pyridin-2-yl]methanol → 3-[5-Chloro-2-(6-trifluoromethyl-pyridin-2-ylmethoxy)-phenoxy]-azetidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/237255

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[6-(Trifluoromethyl)pyridin-2-yl]methanolHCID 14761464—
Reactant3-(5-Chloro-2-hydroxy-phenoxy)-azetidine-1-carboxylic acid tert-butyl esterHCID 67342909—
Product3-[5-Chloro-2-(6-trifluoromethyl-pyridin-2-ylmethoxy)-phenoxy]-azetidine-1-carboxylic acid tert-butyl esterHCID 67346103—

Reaction Steps

Prepared from the title compound of Step A and 3-(5-Chloro-2-hydroxy-phenoxy)-azetidine-1-carboxylic acid tert-butyl ester using general procedure 7.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08642583B2
Source datasetuspto-grants-2014_02
ORD IDord-ea259660f80349a780f6e0ca244905f9
Source noteuspto-grants-2014_02