Nitrogen → HCID 14833063, compound

Participants

Reaction Conditions

Reaction Steps

All operations are carried out under a blanket of N2. 1 mol of each of NaHCO3 and piperidine are introduced into 0.8 1 of water, and 0.5 mol of cyanuric chloride is added in portions at room temperature sufficiently slowly that the reaction temperature is 20° C. and the pH is between 7 and 11. The reaction mixture is subsequently stirred at 20° C. for a further 100 minutes and refluxed for 30 minutes. After cooling, 0.25 mol of each of piperazine and Na2CO3 as 13% strength by weight and 20% strength by weight aqueous solutions respectively are added simultaneously, and the mixture is stirred at room temperature for a further 2 hours and refluxed for 17 hours. The resultant suspension is filtered with suction, washed with water and the residue is dried to constant weight. A finely crystalline, white powder is obtained.

Provenance & Evidence