HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boc-Lys(Z)-OH → Nalpha-tert-butoxycarbonyl-Nepsilon-carbobenzoxy-L-lysyl-N-(indan-2-yl)glycine tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boc-Lys(Z)-OH | HCID 2724765 | — |
| Reactant | tert-butyl 2-[(2,3-dihydro-1H-inden-2-yl)amino]acetate | HCID 13132278 | — |
| Product | Nalpha-tert-butoxycarbonyl-Nepsilon-carbobenzoxy-L-lysyl-N-(indan-2-yl)glycine tert-butyl ester | HCID 13132294 | 69.3% |
Reaction Steps
By reacting 8.2 g of N-(indan-2-yl)glycine tert-butyl ester with 113 g of Nα -tert-butoxycarbonyl-Nε -carbobenzoxy-L-lysine as in Reference Example 5, there is obtained 14 g of Nα -tert-butoxycarbonyl-Nε -carbobenzoxy-L-lysyl-N-(indan-2-yl)glycine tert-butyl ester as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05098892 |
| Source dataset | uspto-grants-1992_03 |
| ORD ID | ord-3243c4cd8cff4fa586c9d0504e264744 |
| Source note | uspto-grants-1992_03 |