HCID 13132289, compound → HCID 53710812, compound

HRID 2372601Notes

Reaction equation

HRID 2372601 reaction equation
C(O)(=O)C(O)=O.[C:7]([O:11][C:12](=[O:29])[CH2:13][N:14]([C:24](=[O:28])[C@H:25]([CH3:27])[NH2:26])[CH:15]1[CH2:23][C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16]1)([CH3:10])([CH3:9])[CH3:8].[CH2:30]([N-:34][C:35](=[O:46])[C:36](=O)[CH2:37][CH2:38][C:39]1[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=1)[CH2:31][CH2:32][CH3:33]>>[C:7]([O:11][C:12](=[O:29])[CH2:13][N:14]([C:24](=[O:28])[C@H:25]([CH3:27])[NH:26][CH:36]([C:35]([NH:34][CH2:30][CH2:31][CH2:32][CH3:33])=[O:46])[CH2:37][CH2:38][C:39]1[CH:40]=[CH:41][CH:42]=[CH:43][CH:44]=1)[CH:15]1[CH2:23][C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16]1)([CH3:8])([CH3:10])[CH3:9]

Participants

3

Reactant 2

HCID 13132289HCID 13132289, compoundHCID 178449531HCID 178449531, compound

Product 1

HCID 53710812HCID 53710812, compoundYield 19.1%

Procedure

By reacting L-alanyl-N-(indan-2-yl)glycine tert-butyl ester oxalate (2.0 g) with N-butyl-2-oxo-4-phenylbutyrylamide (4.0 g) in a similar manner to that of Example 2, there is obtained N-(1-butylaminocarbonyl-3-phenylpropyl)-L-alanyl-N-(indan-2-yl)glycine tert-butyl ester (0.5 g) as colorless oil.

Sources & evidence

ORD record
ord-319616bdd181409299cdd635f402fb93
Source dataset
uspto-grants-1992_03
Patent number
US05098892

Reaction notes

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