反应详情

1.17 g (5 mmol) of 2-phenyl-quinoline-8-aldehyde are boiled in 10 ml of ethanol with 0.9 g (8.75 mmol) of nitroacetone, 0.72 g (5 mmol) of ispropyl 3-aminocrotonate and 0.3 ml (5 mmol) of acetic acid for 1 hour. The precipitated crystals are filtered with suction after cooling and washed with ethanol. 1.1 g of orange-colored crystals of melting point 205° C. are obtained.

1. filtrationThe precipitated crystals are filtered with suction
2. temperatureafter cooling
3. washwashed with ethanol