HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 2-Butyl-4-chloro-6-methylpyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 2-Butyl-6-methyl-4-pyrimidinol | HCID 135424377 | — |
| Product | 2-Butyl-4-chloro-6-methylpyrimidine | HCID 17606408 | — |
Reaction Steps
The pyrimidinone from Example 3 2-n-butyl-6-methylpyrimidin-4(3H)-one is converted to the title compound upon treatment with phosphoryl chloride as described by Gabriel amd Colman (Ber. 1899, 32, 2921) and by Marshall and Walker (J. Chem. Soc., 1951, 1004).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05100897 |
| Source dataset | uspto-grants-1992_03 |
| ORD ID | ord-4c1862e115cb4fe79b223dce9e83a049 |
| Source note | uspto-grants-1992_03 |