Hydrochloric Acid → HCID 178442854, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 1000 ml of ethylene glycol monoethyl ether, 120 g of 3-aminocrotonitrile and 365 g of N-cyanoacetyl-N'-stearoylhydrazine was heated to 135° C. within 2 hours and then refluxed for a further 2 hours. Addition of 150 g of anhydrous zinc chloride and boiling for a further 4 hours were followed by dilution of the melt with 2000 ml of water and addition of 200 ml of 12 % by weight hydrochloric acid. The precipitated product was filtered off with suction, washed with water and dried at 80° C. under reduced pressure. 397 g of 6-cyano-2-heptadecyl-7-hydroxy-5-methyl[1,2,4]triazolo[2,3-a]pyridine were obtained. The compound melts at 274 to 275° C. after recrystallization from acetic acid and has the following analysis:

Provenance & Evidence