HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3,4-tri-O-acetyl-5-thio-alpha-xylopyranosyl bromide → 3-cyanophenyl 2,3,4-tri-O-acetyl-1,5-dithio-beta-D-xylopyranoside
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3,4-tri-O-acetyl-5-thio-alpha-xylopyranosyl bromide | HCID 10926314 | — |
| Reactant | 3-Sulfanylbenzonitrile | HCID 14795334 | — |
| Catalyst | Zinc Oxide | HCID 3007857 | — |
| Product | 3-cyanophenyl 2,3,4-tri-O-acetyl-1,5-dithio-beta-D-xylopyranoside | HCID 14795343 | 31% |
Reaction Steps
If the procedure described in Preparation IV is followed starting from 10.3 g (74.1.10-3 mol) of 3-mercaptobenzonitrile, 28.94 g (81.5.10-3 mol) of 2,3,4-tri-O-acetyl-5-thio-α-D-xylopyranosyl bromide and 6.05 g (74.3.10-3 mol) of zinc oxide (ZnO), 9.6 g (yield: 31%) of the expected product are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05101048 |
| Source dataset | uspto-grants-1992_03 |
| ORD ID | ord-adb8a86e4ee441c385cd2540af728447 |
| Source note | uspto-grants-1992_03 |