HuagongsheHuagongshe Chemistry Print Report · For research reference only
Mercuric cyanide → 4-(4-cyanophenyl)phenyl 2,3,4-tri-O-acetyl-1,5-dithio-beta-D-xylopyranoside
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Mercuric cyanide | HCID 11591 | — |
| Reactant | 2,3,4-tri-O-acetyl-5-thio-alpha-xylopyranosyl bromide | HCID 10926314 | — |
| Reactant | 4'-Mercaptobiphenyl-4-carbonitrile | HCID 14795335 | — |
| Product | 4-(4-cyanophenyl)phenyl 2,3,4-tri-O-acetyl-1,5-dithio-beta-D-xylopyranoside | HCID 14795359 | 10.2% |
Reaction Steps
If the procedure described in Preparation I is followed starting from 2.3 g (10.9.10-3 mol) of 4-(4-mercaptophenyl)benzonitrile, 4.26 g (11.9.10-3 mol) of 2,3,4-tri-O-acetyl-5-thio-α-D-xylopyranosyl bromide and 2.75 g (10.9.10-3 mol) of mercuric cyanide (Hg(CN)2), 0.540 g (yield: 10%) of the expected product is obtained after purification by flash chromatography using methylene chloride as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05101048 |
| Source dataset | uspto-grants-1992_03 |
| ORD ID | ord-d5723ec11cee4403b39205923fcd61ca |
| Source note | uspto-grants-1992_03 |