HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-Hydroxyacetophenone → 4-acetylphenyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylopyranoside
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-Hydroxyacetophenone | HCID 7469 | — |
| Reactant | Boron trifluoride etherate | HCID 8000 | — |
| Reactant | 2,3,4-tri-O-acetyl-5-thio-alpha-D-xylopyranosyl trichloroacetimidate | HCID 21631547 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-acetylphenyl 2,3,4-tri-O-acetyl-5-thio-beta-D-xylopyranoside | HCID 15067850 | 47% |
Reaction Steps
If the procedure described in Preparation LXXXI is followed starting from 380 mg (0.882.10-3 mol) of 2,3,4-tri-O-acetyl-5-thio-α-D-xylopyranosyl trichloroacetimidate, 100 mg (73.5.10-3 mol) of 1-(4-hydroxyphenyl)ethanone and 1.47 ml of a 0.1M solution of boron trifluoride etherate in methylene chloride, 140 mg (yield: 47%) of the expected product are obtained after crystallization from ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05101048 |
| Source dataset | uspto-grants-1992_03 |
| ORD ID | ord-c751c99571464f24a8a5fb8fcdbfbc5b |
| Source note | uspto-grants-1992_03 |