Sodium Methoxide → 2-acetylphenyl 5-thio-beta-D-xylopyranoside

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Reaction Steps

If the procedure described in Preparation LXXXIV is followed starting from 0.88 g (2.1.10-3 mol) of 2-acetylphenyl 2,3,4-tri-O-acetyl-5-thio-β-D-xylopyranoside and 0.1 ml of a solution of sodium methylate in methanol (8% w/v of Na), reacted in 50 ml of methanol for 30 min, 0.51 g (yield: 84%) of the expected product is obtained after purification by chromatography on silica gel using a chloroform/methanol mixture (12/1 v/v) as the eluent, and lyophilization.

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