Phenyl isocyanate → HCID 54423781, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 1.0 g of 9-trimethylsilyl-9-fluorenemethanol and 0.4 mL of phenyl isocyanate in 2.0 mL of dry benzene was heated in an oil bath at 80° C. for seven hours. The mixture was cooled to room temperature and triturated with 20 mL of Skelly F. The crystals deposited were removed by filtration, rinsed with Skelly F, and recrystallized from Skelly B to give 1.31 g (91.9%) of the urethane as white crystals, m.p. 137°-138° C.; IR(KBr): 3300 (NH), 1700 (C=O) cm-1 ; 1H NMR (CDCl3) 5 -0.12 (s, 9H, SiMe3), 5.07 (s, 2H, CH2), 6.21 (b, 1H, NH), 6.80-8.00 (m, 13H, aryl).

Provenance & Evidence