Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | HCID 58181382 | HCID 58181382 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 58181659 | HCID 58181659 | — |
Reaction Steps
Compound 93-1 (350 mg, 0.932 mmol) was dissolved in CH2Cl2 (4.66 ml) and cooled to 0° C., Ac2O (0.176 ml, 2 eq), pyridine (0.151 ml, 2 eq), and DMAP (11 mg, 0.1 eq) was added. The mixture was stirred for 2 hours, diluted with EtOAc, washed with CuSO4 solution, water, dried and concentrated to give 370 mg of compound 93-2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08642582B2 |
|---|
| Source dataset | uspto-grants-2014_02 |
|---|
| ORD ID | ord-5098cfe2de234066a55e2d94c9a52937 |
|---|
| Source note | uspto-grants-2014_02 |
|---|
