HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Ethyl-3-nitropyridin-4-amine → 4-N-ethylpyridine-3,4-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Ethyl-3-nitropyridin-4-amine | HCID 21937597 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-N-ethylpyridine-3,4-diamine | HCID 12036392 | 94% |
Reaction Steps
Ethyl-(3-nitropyridin-4-yl)amine (8.7 g, 52.0 mmol) in ethanol (150 ml) was hydrogenated for 18 hours in the presence of 10% palladium on carbon. After filtration of the catalyst through celite, the filtrate was concentrated in vacuo to afford the title compound (6.7 g, 94%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07459454B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-aab4d94a430d4c42b783a30dc1dd496d |
| Source note | uspto-grants-2008_12 |