3-Fluorophenylboronic acid → HCID 69153961, compound

HRID 2373194Notes

Reaction equation

HRID 2373194 reaction equation
[C:1]([C:4]1[C:9]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[N:8][N:7]([CH3:16])[C:6](=[O:17])[C:5]=1[NH2:18])(=[O:3])[CH3:2].[F:19][C:20]1[CH:21]=[C:22](B(O)O)[CH:23]=[CH:24][CH:25]=1>>[C:1]([C:4]1[C:9]([C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=2)=[N:8][N:7]([CH3:16])[C:6](=[O:17])[C:5]=1[NH:18][C:24]1[CH:23]=[CH:22][CH:21]=[C:20]([F:19])[CH:25]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 27339863-Fluorophenylboronic acidHCID 13811517HCID 13811517, compound

Product 1

HCID 69153961HCID 69153961, compound

Procedure

The title compound was synthesized from 5-acetyl-4-amino-2-methyl-6-phenylpyridazin-3(2H)-one (Dal Piaz, V., Ciciani, G, Giovannoni, M. P., Heterocycles, 1991, 32, 1173-9) and the corresponding 3-fluorophenylboronic acid following the procedure of Example 1.

Sources & evidence

ORD record
ord-cb64398f8a6b4bfa837c3f1489544664
Source dataset
uspto-grants-2008_12
Patent number
US07459453B2

Reaction notes

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