Pyridine → HCID 86602410, compound

Participants

Reaction Steps

To a solution of 4-(5-bromo-3-pyridyl)-1-ethyl-6-methyl-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde (34 mg) in DMF (1 ml) was added pyridine (0.032 ml) and hydroxylamine hydrochloride (13.7 mg) at room temperature and the mixture was stirred at room temperature for 2 hours. The reaction mixture was diluted with water and extracted with EtOAc. The organic layer was washed with water, brine, dried over anhydrous MgSO4 and concentrated in vacuo to give 4-(5-bromo-3-pyridyl)-1-ethyl-6-methyl-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde oxime (35 mg) as a yellow crystal.

Provenance & Evidence