HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-N,N-diethylbenzamide → 3-[2-hydroxy-3-(pyrrolidin-1-yl)propyl]-2H-isoquinolin-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-N,N-diethylbenzamide | HCID 75945 | — |
| Reactant | 3-Hydroxy-4-(pyrrolidin-1-yl)butyronitrile | HCID 23082088 | — |
| Product | 3-[2-hydroxy-3-(pyrrolidin-1-yl)propyl]-2H-isoquinolin-1-one | HCID 10445941 | 3.3% |
Reaction Steps
By the reaction in the same manner as in Example 1a, using N,N-diethyl-2-methylbenzamide (1.91 g) and 3-hydroxy-4-(pyrrolidin-1-yl)butyronitrile (1.54 g), 3-[2-hydroxy-3-(pyrrolidin-1-yl)propyl]-2H-isoquinolin-1-one (0.089 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07459465B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-f2a941c7faf642d6be848197f09090dc |
| Source note | uspto-grants-2008_12 |