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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2373280Generated: October 30, 2026

Hydrochloric Acid → (R)-3-[2-(2-hydroxymethylpyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one hydrochloride dihydrate

https://huagongshe.com/reaction/2373280

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant(R)-3-(2-(2-(hydroxymethyl)pyrrolidin-1-yl)ethyl)-5-methylisoquinolin-1(2H)-oneHCID 10424118—
Product(R)-3-[2-(2-hydroxymethylpyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one hydrochloride dihydrateHCID 67221092—

Reaction Steps

Using a known method, (R)-3-[2-(2-hydroxymethylpyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one was converted to a hydrochloride to give (R)-3-[2-(2-hydroxymethylpyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one hydrochloride dihydrate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07459465B2
Source datasetuspto-grants-2008_12
ORD IDord-a17ddabe6d0f457d9b8add5c865410e4
Source noteuspto-grants-2008_12