HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-fluoro-2,3,4,5-tetrahydro-1H-1-benzazepine-2,5-dione → 4-Dimethylaminomethylene-8-methyl-3,4-dihydro-1H-benzo[b]azepine-2,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-fluoro-2,3,4,5-tetrahydro-1H-1-benzazepine-2,5-dione | HCID 23440936 | — |
| Reactant | 8-methyl-3,4-dihydro-1H-1-benzazepine-2,5-dione | HCID 58476639 | — |
| Reactant | 4-dimethylamino-methylene-7-methoxy-3,4-dihydro-1H-benzo[b]azepine-2,5-dione | HCID 66934777 | — |
| Product | 4-Dimethylaminomethylene-8-methyl-3,4-dihydro-1H-benzo[b]azepine-2,5-dione | HCID 66934566 | — |
Reaction Steps
In a manner similar to that described above for 4-dimethylamino-methylene-7-methoxy-3,4-dihydro-1H-benzo[b]azepine-2,5-dione, 7-fluoro-3,4-dihydro-1H-benzo[b]azepine-2,5-dione, 0.64 g of 8-methyl-3,4-dihydro-1H-benzo[b]azepine-2,5-dione was converted to v-g (87%): MS m/z═245 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07459448B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-1a260e314b82497ab21999e54bb23ad7 |
| Source note | uspto-grants-2008_12 |