Triethylamine → HCID 178459242, compound

Participants

Reaction Steps

To a solution of trans-8-chloro-1-(4-isopropoxy-cyclohexyl)-5,6-dihydro-4H-2,3,5,10b-tetraaza-benzo[e]azulene hydrochloride (0.070 g, 0.18 mmol) and triethylamine (0.037 ml, 0.26 mmol) in dichloromethane (3 ml) was added N,N-dimethylsulfamoyl chloride (0.028 ml, 0.26 mmol) at room temperature. After stirring for 65 h the reaction mixture was concentrated in vacuo. Flash-chromatography with n-heptane/2-propanol as eluent gave the title compound (0.063 g, 77%) as white solid. MS m/e: 468 (M+H+).

Provenance & Evidence