HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Z)-6-dimethylaminomethylene-6,7-dihydro-9H-pyrido[2,3-b]azepine-5,8-dione → 2-(3,4-Dimethoxy-phenylamino)-5,7-dihydro-1,3,7,8-tetraaza-dibenzo[a,c]cyclohepten-6-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Z)-6-dimethylaminomethylene-6,7-dihydro-9H-pyrido[2,3-b]azepine-5,8-dione | HCID 66934793 | — |
| Reactant | N-(3,4-dimethoxyphenyl)guanidine | HCID 178492306 | — |
| Product | 2-(3,4-Dimethoxy-phenylamino)-5,7-dihydro-1,3,7,8-tetraaza-dibenzo[a,c]cyclohepten-6-one | HCID 11689098 | — |
Reaction Steps
In a manner similar to method H (NaHCO3 used in place of K2CO3) (Z)-6-dimethylaminomethylene-6,7-dihydro-9H-pyrido[2,3-b]azepine-5,8-dione (v-h) and 1-(3,4-dimethoxyphenyl)guanidine were converted to I-1 (85%): MS Rt═1.3 min. m/z 364 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07459448B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-87a3ad1d99044ee0bc816c165f41863d |
| Source note | uspto-grants-2008_12 |