HuagongsheHuagongshe Chemistry Print Report · For research reference only
Guanidine → 2-Amino-10-iodo-5H,7H-benzo[b]pyrimido[4,5-d]azepin-6-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Guanidine | HCID 3520 | — |
| Reactant | 4-dimethylaminomethylene-7-iodo-3,4-dihydro-1H-benzo[b]azepine-2,5-dione | HCID 66935066 | — |
| Product | 2-Amino-10-iodo-5H,7H-benzo[b]pyrimido[4,5-d]azepin-6-one | HCID 59851021 | — |
Reaction Steps
In a manner similar to that described in method H, 7-iodo-4-dimethylaminomethylene-3,4-dihydro-1H-benzo[b]azepine-2,5-dione (v-a) and guanidine were converted to I-51 (79%): HRMS Calcd. for C12H9N4O: 352.9899, Found 352.9900.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07459448B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-f73381d85491465092aa7d6b2d3d57ac |
| Source note | uspto-grants-2008_12 |