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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2373386Generated: October 30, 2026

HCID 66934668, compound → 4-(10-Bromo-6-oxo-6,7-dihydro-5H-benzo[b]pyrimido[4,5-d]azepin-2-ylamino)-benzoic acid

https://huagongshe.com/reaction/2373386

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66934668HCID 66934668—
ReactantHCID 178512548HCID 178512548—
Product4-(10-Bromo-6-oxo-6,7-dihydro-5H-benzo[b]pyrimido[4,5-d]azepin-2-ylamino)-benzoic acidHCID 59851843—

Reaction Steps

In a manner similar to method I, 7-bromo-4-dimethylaminomethylene-3,4-dihydro-1H-benzo[b]azepine-2,5-dione (v-k) and 4-guanidinobenzoic acid were converted to I-25 (22%): HRMS Calcd. for C19H13BrN4O3: 425.0249, Found 425.0269.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07459448B2
Source datasetuspto-grants-2008_12
ORD IDord-1430d7897f7a40d3a115f477011d1e8f
Source noteuspto-grants-2008_12