1-Ethoxy-4-iodobenzene → 7-(4-Ethoxy-phenylethynyl)-3,3-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepine

HRID 2373447Notes

Reaction equation

HRID 2373447 reaction equation
[C:1]([C:3]1[CH:15]=[CH:14][C:6]2[O:7][CH2:8][C:9]([CH3:13])([CH3:12])[CH2:10][O:11][C:5]=2[CH:4]=1)#[CH:2].[CH2:16]([O:18][C:19]1[CH:24]=[CH:23][C:22](I)=[CH:21][CH:20]=1)[CH3:17]>>[CH2:16]([O:18][C:19]1[CH:24]=[CH:23][C:22]([C:2]#[C:1][C:3]2[CH:15]=[CH:14][C:6]3[O:7][CH2:8][C:9]([CH3:12])([CH3:13])[CH2:10][O:11][C:5]=3[CH:4]=2)=[CH:21][CH:20]=1)[CH3:17]

Participants

3

Reactant 2

HCID 2207001-Ethoxy-4-iodobenzeneHCID 598526957-Ethynyl-3,3-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepine

Product 1

HCID 113478397-(4-Ethoxy-phenylethynyl)-3,3-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepine

Procedure

The title compound is prepared in analogy to example 1 from 7-ethynyl-3,3-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepine (6) (example 1d) and 1-ethoxy-4-iodo-benzene. MS (ESI) 322.2 (M•)+.

Sources & evidence

ORD record
ord-8944a8a5fa8b4e3f8da682d235a78700
Source dataset
uspto-grants-2008_12
Patent number
US07459480B2

Reaction notes

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