1-Iodo-3,4-methylenedioxybenzene → 7-Benzo[1,3]dioxol-5-ylethynyl-3,3-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepine

HRID 2373448Notes

Reaction equation

HRID 2373448 reaction equation
[C:1]([C:3]1[CH:15]=[CH:14][C:6]2[O:7][CH2:8][C:9]([CH3:13])([CH3:12])[CH2:10][O:11][C:5]=2[CH:4]=1)#[CH:2].I[C:17]1[CH:25]=[CH:24][C:20]2[O:21][CH2:22][O:23][C:19]=2[CH:18]=1>>[O:21]1[C:20]2[CH:24]=[CH:25][C:17]([C:2]#[C:1][C:3]3[CH:15]=[CH:14][C:6]4[O:7][CH2:8][C:9]([CH3:12])([CH3:13])[CH2:10][O:11][C:5]=4[CH:4]=3)=[CH:18][C:19]=2[O:23][CH2:22]1

Participants

3

Reactant 2

HCID 1386201-Iodo-3,4-methylenedioxybenzeneHCID 598526957-Ethynyl-3,3-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepine

Product 1

HCID 692924337-Benzo[1,3]dioxol-5-ylethynyl-3,3-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepine

Procedure

The title compound is prepared in analogy to example 1 from 7-ethynyl-3,3-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepine (6) (example 1d) and 5-iodo-benzo[1,3]dioxole. MS (ESI) 322.2 (M•)+.

Sources & evidence

ORD record
ord-5bb3bc83a00d45e9b35fac043a8abc6b
Source dataset
uspto-grants-2008_12
Patent number
US07459480B2

Reaction notes

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