Ethyl 6-chloronicotinate → HCID 11291073, compound

HRID 2373450Notes

Reaction equation

HRID 2373450 reaction equation
[C:1]([C:3]1[CH:15]=[CH:14][C:6]2[O:7][CH2:8][C:9]([CH3:13])([CH3:12])[CH2:10][O:11][C:5]=2[CH:4]=1)#[CH:2].Cl[C:17]1[CH:27]=[CH:26][C:20]([C:21]([O:23][CH2:24][CH3:25])=[O:22])=[CH:19][N:18]=1>>[CH2:24]([O:23][C:21](=[O:22])[C:20]1[CH:26]=[CH:27][C:17]([C:2]#[C:1][C:3]2[CH:15]=[CH:14][C:6]3[O:7][CH2:8][C:9]([CH3:12])([CH3:13])[CH2:10][O:11][C:5]=3[CH:4]=2)=[N:18][CH:19]=1)[CH3:25]

Participants

3

Reactant 2

HCID 2799611Ethyl 6-chloronicotinateHCID 598526957-Ethynyl-3,3-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepine

Product 1

HCID 11291073HCID 11291073, compound

Procedure

The title compound is prepared in analogy to example 1 from 7-ethynyl-3,3-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepine (6) (example 1d) and ethyl 6-chloro-nicotinate. MS (ESI) 352.4 (M+H)+.

Sources & evidence

ORD record
ord-03dc77a2297640aaaac447d1c8f59723
Source dataset
uspto-grants-2008_12
Patent number
US07459480B2

Reaction notes

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