HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11462234, compound → 4-(3,3-Dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-ylethynyl)-N,N-dimethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11462234 | HCID 11462234 | — |
| Reactant | 4-ethynyl-N,N-dimethylbenzamide | HCID 20253928 | — |
| Reactant | 7-iodo-3,3-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepine | HCID 59852691 | — |
| Product | 4-(3,3-Dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-ylethynyl)-N,N-dimethyl-benzamide | HCID 69292432 | — |
Reaction Steps
The title compound is prepared in analogy to 3-(3,3-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-ylethynyl)-benzoic acid ethyl ester (10) from 4-ethynyl-N,N-dimethyl-benzamide and 7-iodo-3,3-dimethyl-3,4-dihydro-2H-benzo[b][1,4]dioxepine (5) as a light brown solid, MS (ESI) 699.4 (100, [2M+H]+), 350.4 (15, [M+H]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07459480B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-d3302cd16dd1472096a25188900f5a8d |
| Source note | uspto-grants-2008_12 |