HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178499077, compound → HCID 178499078, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178499077 | HCID 178499077 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Solvent | Palladium | HCID 23938 | — |
| Product | HCID 178499078 | HCID 178499078 | — |
Reaction Steps
1-benzyl 4-tert-butyl 2-[5-(benzoyloxy)-4-hydroxy-6-(methoxycarbonyl)pyrimidin-2-yl]-2-methylpiperazine-1,4-dicarboxylate (C-43) was dissolved in AcOEt and hydrogenated at 1 atm on 10% (w/w) Pd/C over night. After filtration of the catalyst, solvent was evaporated to give the crude title compound (C-44).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07459452B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-4803e41fa4a447d585420110ab665fdc |
| Source note | uspto-grants-2008_12 |