HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178481086, compound → HCID 178480807, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178481086 | HCID 178481086 | — |
| Solvent | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| Product | HCID 178480807 | HCID 178480807 | — |
Reaction Steps
Crude material tert-butyl 3-(4-{[(4-fluorobenzyl)amino]carbonyl}-5,6-dihydroxypyrimidin-2-yl)-3,4-dimethylpiperazine-1-carboxylate (C-46) was stirred in DCM/TFA (1:1) for 1 hour. Evaporation of the solvent afforded the crude title compound (C-47).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07459452B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-fc24760b70f043739ea3ca07021838bf |
| Source note | uspto-grants-2008_12 |