反应详情

To a 1 L 4-necked round bottom flask was added 10.0 g (0.045 mol) of 10-methoxyiminostilbene, 150.0 ml of dichloromethane, 37.0 g (0.57 mol) of sodium cyanate and 15.0 g (0.13 moles) of maleic acid and stirred at room temperature. The contents were heated to reflux (40-45° C.) under vigorous stirring for about 6 to about 8 hours. After completion of the reaction (detected by TLC) the reaction mass was filtered and washed with 50.0 ml dichloromethane. The dichloromethane layer was washed with water (50.0 ml×2) and the layers were separated.

1. temperatureThe contents were heated
2. temperatureto reflux (40-45° C.)
3. stirringunder vigorous stirring for about 6 to about 8 hours
4. customAfter completion of the reaction (detected by TLC) the reaction mass
5. filtrationwas filtered
6. washwashed with 50.0 ml dichloromethane
7. washThe dichloromethane layer was washed with water (50.0 ml×2)
8. customthe layers were separated