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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2373556Generated: October 30, 2026

Acetyl chloride → N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)acetamide

https://huagongshe.com/reaction/2373556

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetyl chlorideHCID 6367—
Reactant3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}anilineHCID 49852105—
ProductN-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)acetamideHCID 4985087252%

Reaction Steps

The title compound was prepared in 52% yield according to the general procedure for the preparation of the amides (Method B) starting from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and acetyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07459456B2
Source datasetuspto-grants-2008_12
ORD IDord-575fc817af9848b6af77c24762937fa0
Source noteuspto-grants-2008_12